1,3-Dihydroxyacetone Hanyoyin Samar da Ayyuka da Gabatarwar Aikace-aikace CAS 96-26-4

1,3-Dihydroxyacetone Gabatarwa

1,3-Dihydroxyacetone wani fili ne na kwayoyin halitta tare da tsarin kwayoyin C3H6O3, wanda shine polyhydroxyketose da ketose mafi sauki.Fitowar farin lu'ulu'u ne mai farin foda, mai sauƙin narkewa a cikin kaushi na halitta kamar ruwa, ethanol, ether, da acetone.Matsayin narkewa shine 75-80 ℃, kuma ruwa mai narkewa shine> 250g / L (20 ℃).Yana da ɗanɗano mai daɗi kuma yana da ƙarfi a pH 6.0.1,3-Dihydroxyacetone shine rage sukari.Duk monosaccharides (idan dai akwai aldehyde kyauta ko ketone carbonyl kungiyoyin) suna da raguwa.Dihydroxyacetone ya hadu da abubuwan da ke sama, saboda haka yana cikin nau'in rage sukari.

Akwai galibi hanyoyin haɗin sinadarai da hanyoyin haɗewar ƙwayoyin cuta.Akwai manyan hanyoyin sinadarai guda uku don 1,3-dihydroxyacetone: electrocatalysis, ƙarfe catalytic oxidation, da formaldehyde condensation.Samar da sinadarai na 1,3-dihydroxyacetone har yanzu yana cikin matakin bincike na dakin gwaje-gwaje.Samar da 1,3-dihydroxyacetone ta hanyar nazarin halittu yana da fa'ida mai mahimmanci: babban samfurin samfurin, babban canjin glycerol da ƙananan farashin samarwa.Samar da 1,3-dihydroxyacetone a cikin china da ƙasashen waje galibi yana ɗaukar hanyar juzu'in microbial na glycerol.

Hanyar hada sinadarai

1. 1,3-dihydroxyacetone an haɗa shi daga 1,3-dichloroacetone da ethylene glycol a matsayin babban kayan albarkatun kasa ta hanyar kariya ta carbonyl, etherification, hydrogenolysis, da hydrolysis.1,3-dichloroacetone da ethylene glycol suna mai zafi kuma sun sake dawowa a cikin toluene don samar da 2,2-dichloromethyl-1,3-dioxolane.Sai su amsa tare da sodium benzylidene a cikin N, N-dimethylformamide don samar da 2,2-dibenzyloxy-1,3-dioxolane, wanda aka sanya hydrogenated a karkashin Pd / C catalysis don hada 1,3-dioxolane-2,2-dimethanol, wanda. sai a sanya ruwa a cikin hydrochloric acid don samar da 1,3-dihydroxyacetone.Kayan albarkatun kasa don haɗakar da 1,3-dihydroxyacetone ta amfani da wannan hanya yana da sauƙi don samun, yanayin amsawa yana da sauƙi, kuma ana iya sake yin amfani da Pd / C mai haɓakawa, wanda yana da mahimmancin aikace-aikacen.

2. 1,3-dihydroxyacetone an haɗa shi daga 1,3-dichloroacetone da methanol ta hanyar kariya ta carbonyl, etherification, hydrolysis, da halayen hydrolysis.1,3-dichloroacetone yana amsawa tare da wuce haddi mai anhydrous methanol a gaban abin sha don samar da 2,2-dimethoxy-1,3-dichloropropane, wanda aka yi zafi da sodium benzylate a cikin N, N-dimethylformamide don samar da 2,2-dimethoxy -1,3-dibenzyloxypropane.Ana sanya hydrogenated a ƙarƙashin Pd/C catalysis don samar da 2,2-dimethoxy-1,3-propanediol, wanda aka sanya shi cikin hydrochloric acid don samar da 1,3-dihydroxyacetone.Wannan hanya ta maye gurbin mai kare carbonyl daga ethylene glycol zuwa methanol, yana sa ya fi sauƙi don rabuwa da tsaftace samfurin 1,3-dihydroxyacetone, wanda ke da mahimmancin ci gaba da ƙimar aikace-aikacen.

3. Ƙaddamar da 1,3-dihydroxyacetone ta amfani da acetone, methanol, chlorine ko bromine a matsayin babban kayan albarkatun kasa.Ana amfani da acetone, methanol anhydrous, da chlorine gas ko bromine don samar da 2,2-dimethoxy-1,3-dichloropropane ko 1,3-dibromo-2,2-dimethoxypropane ta hanyar tukunyar tukunya ɗaya.Daga nan sai a shafe su da sodium benzylate don samar da 2,2-dimethoxy-1,3-dibenzyloxypropane, wanda aka sanya shi hydrogenated da hydrolyzed don samar da 1,3-dihydroxyacetone.Wannan hanya tana da yanayi mai sauƙi, kuma amsawar "tukunya ɗaya" yana guje wa amfani da 1,3-dichloroacetone mai tsada da ban haushi, yana mai da shi ƙasa da ƙima sosai don haɓakawa.

Aikace-aikace

1,3-Dihydroxyacetone shine ketose da ke faruwa a zahiri wanda ke da lalacewa, mai narkewa, kuma mara guba ga jikin ɗan adam da muhalli.Yana da ƙari mai yawa wanda za'a iya amfani dashi a cikin kayan shafawa, magunguna, da masana'antun abinci.

Ana amfani dashi a cikin masana'antar kayan shafawa

1,3-Dihydroxyacetone an fi amfani dashi azaman sinadari a cikin kayan kwalliya, musamman azaman kayan kariya na rana tare da sakamako na musamman, wanda zai iya hana zubar da danshi mai yawa na fata, kuma yana taka rawa wajen yin moisturizing, kariya daga rana, da kariya ta UV.Bugu da ƙari, ƙungiyoyin aikin ketone a cikin DHA na iya amsawa tare da amino acid da ƙungiyoyin amino keratin na fata don samar da polymer mai launin ruwan kasa, yana sa fatar mutane ta samar da launin ruwan kasa na wucin gadi.Sabili da haka, ana iya amfani da shi azaman simulant don fitowar rana don samun fata mai launin ruwan kasa ko launin ruwan kasa wanda yayi kama da sakamakon dogon lokaci zuwa hasken rana, yana sa ta yi kyau.

Inganta yawan nama maras kyau na aladu

1,3-Dihydroxyacetone shine samfurin matsakaici na sukari metabolism, yana taka muhimmiyar rawa a cikin aiwatar da metabolism na sukari, rage kitsen jikin alade da inganta yawan nama mara nauyi.Ma'aikatan kimiyya da fasaha na Japan sun nuna ta hanyar gwaje-gwajen cewa ƙara wani adadin DHA da cakuda pyruvate (gishiri na calcium) a cikin abincin alade (a cikin nauyin 3: 1) na iya rage kitsen naman alade da kashi 12% zuwa 15%, da kuma kitsen naman ƙafafu da tsoka mafi tsayi na baya shima an rage shi daidai, tare da haɓaka abun ciki na furotin.

Don abinci mai aiki

Ƙarin 1,3-dihydroxyacetone (musamman a hade tare da pyruvate) zai iya inganta yanayin rayuwa na jiki da kuma fatty acid oxidation, mai yiwuwa mai tasiri mai ƙona kitse don rage kitsen jiki da jinkirta samun nauyi (sakamakon asarar nauyi), da rage yawan abin da ya faru na cututtuka masu alaka.Hakanan yana iya inganta haɓakar insulin da rage matakin cholesterol na plasma da ke haifar da babban abincin cholesterol.Dogon lokaci kari zai iya ƙara yawan amfani da sukari na jini da kuma adana tsoka glycogen, Ga 'yan wasa, zai iya inganta aikin jimiri na aerobic.

Sauran amfani

1,3-dihydroxyacetone kuma za a iya amfani dashi kai tsaye azaman reagent antiviral.Misali, a al'adar amfrayo kaji, amfani da DHA na iya hana kamuwa da kwayar cutar kaji sosai, yana kashe kashi 51% zuwa 100% na kwayar cutar.A cikin masana'antar fata, ana iya amfani da DHA azaman wakili na kariya ga samfuran fata.Bugu da ƙari, ana iya amfani da abubuwan kiyayewa da suka ƙunshi DHA don adanawa da adana 'ya'yan itatuwa da kayan marmari, kayayyakin ruwa, da nama.